Effect of glutamine on Th1 and Th2 cytokine responses of human peripheral blood mononuclear cells
WK Chang, KD Yang, MF Shaio - Clinical Immunology, 1999 - Elsevier
Decreased glutamine concentrations are found in patients with catabolic stress and are
related to susceptibility to infections. In this study, we evaluated the role of glutamine in
Th1/Th2 cytokine responses. Peripheral blood mononuclear cells were stimulated with
phytohemagglutinin (PHA), live attenuated bacillus Calmette-Guérin (BCG), or measles virus
in the presence of different glutamine concentrations. We found that glutamine at an optimal
concentration (0.6 mM) significantly enhanced PHA-stimulated lymphocyte proliferation as …
related to susceptibility to infections. In this study, we evaluated the role of glutamine in
Th1/Th2 cytokine responses. Peripheral blood mononuclear cells were stimulated with
phytohemagglutinin (PHA), live attenuated bacillus Calmette-Guérin (BCG), or measles virus
in the presence of different glutamine concentrations. We found that glutamine at an optimal
concentration (0.6 mM) significantly enhanced PHA-stimulated lymphocyte proliferation as …