Adenosine kinase gene expression in human colorectal cancer
S Giglioni, R Leoncini, E Aceto, A Chessa… - … , and Nucleic Acids, 2008 - Taylor & Francis
S Giglioni, R Leoncini, E Aceto, A Chessa, S Civitelli, A Bernini, G Tanzini, F Carraro…
Nucleosides, Nucleotides, and Nucleic Acids, 2008•Taylor & FrancisReal-time reverse transcription polymerase chain reaction (qRT-PCR) was used to evaluate
gene expression of adenosine kinase, a key enzyme in adenosine metabolism, in human
intestinal biopsy specimens of 10 colorectal cancer patients. Quantitative mRNA expression
levels were normalized against the reference gene β-actin. The results showed that
adenosine kinase gene expression was significantly higher in cancer than in normal-
appearing tissue, in line with our previous measurements of adenosine kinase enzyme …
gene expression of adenosine kinase, a key enzyme in adenosine metabolism, in human
intestinal biopsy specimens of 10 colorectal cancer patients. Quantitative mRNA expression
levels were normalized against the reference gene β-actin. The results showed that
adenosine kinase gene expression was significantly higher in cancer than in normal-
appearing tissue, in line with our previous measurements of adenosine kinase enzyme …
Real-time reverse transcription polymerase chain reaction (qRT-PCR) was used to evaluate gene expression of adenosine kinase, a key enzyme in adenosine metabolism, in human intestinal biopsy specimens of 10 colorectal cancer patients. Quantitative mRNA expression levels were normalized against the reference gene β -actin. The results showed that adenosine kinase gene expression was significantly higher in cancer than in normal-appearing tissue, in line with our previous measurements of adenosine kinase enzyme activities in colorectal tumor samples.
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