[HTML][HTML] The Krüppel-like factor KLF2 inhibits peroxisome proliferator-activated receptor-γ expression and adipogenesis

SS Banerjee, MW Feinberg, M Watanabe… - Journal of Biological …, 2003 - ASBMB
Obesity is an important public health problem associated with a number of disease states
such as diabetes and arteriosclerosis. As such, an understanding of the mechanisms
governing adipose tissue differentiation and function is of considerable importance. We
recently reported that the Krüppel-like zinc finger transcription factor KLF15 can induce
adipocyte maturation and GLUT4 expression. In this study, we identify that a second family
member, KLF2/Lung Krüppel-like factor (LKLF), as a negative regulator of adipocyte …