The vascular extracellular matrix (ECM) is essential for the structural integrity of the vessel
wall and also serves as a substrate for the binding and retention of secreted products of
vascular cells as well as molecules coming from the circulation. Although proteomics has
been previously applied to vascular tissues, few studies have specifically targeted the
vascular ECM and its associated proteins. Thus, its detailed composition remains to be
characterized. In this study, we describe a methodology for the extraction of extracellular …