[HTML][HTML] Integrins and cytokines activate nuclear transcription factor-κB in human neutrophils
R Kettritz, M Choi, S Rolle, M Wellner, FC Luft - Journal of Biological …, 2004 - ASBMB
Neutrophil adhesion to extracellular matrix is necessary for an effective inflammatory
response. Adhesion may accelerate neutrophil activation by affecting intracellular signaling
pathways. The nuclear transcription factor κB (NF-κB) controls several cellular functions,
including inflammation, proliferation, and cell survival. We explored the role of adhesion in
NF-κB activation in human neutrophils. Cells were stimulated with tumor necrosis factor-α
(TNF-α), granulocyte macrophage-colony-stimulating factor (GM-CSF), interleukin-8 (IL-8) …
response. Adhesion may accelerate neutrophil activation by affecting intracellular signaling
pathways. The nuclear transcription factor κB (NF-κB) controls several cellular functions,
including inflammation, proliferation, and cell survival. We explored the role of adhesion in
NF-κB activation in human neutrophils. Cells were stimulated with tumor necrosis factor-α
(TNF-α), granulocyte macrophage-colony-stimulating factor (GM-CSF), interleukin-8 (IL-8) …