Use of osmium tetroxide staining with microcomputerized tomography to visualize and quantify bone marrow adipose tissue in vivo

EL Scheller, N Troiano, JN VanHoutan… - Methods in …, 2014 - Elsevier
Adipocytes reside in discrete, well-defined depots throughout the body. In addition to mature
adipocytes, white adipose tissue depots are composed of many cell types, including
macrophages, endothelial cells, fibroblasts, and stromal cells, which together are referred to
as the stromal vascular fraction (SVF). The SVF also contains adipocyte progenitors that give
rise to mature adipocytes in those depots. Marrow adipose tissue (MAT) or marrow fat has
long been known to be present in bone marrow (BM) but its origin, development, and …