Immunological disturbances in the central nervous system linked to MRI findings in multiple sclerosis

HY Wang, M Matsui, T Saida - Journal of neuroimmunology, 2002 - Elsevier
To clarify immunological disturbances in the central nervous system (CNS) in multiple
sclerosis (MS) by linking to magnetic resonance imaging (MRI) findings, 22 patients with
relapsing remitting MS were studied. Cerebrospinal fluid (CSF) samples were analyzed
during a total of 27 independent MS stages (20 active, 7 inactive) on 25 occasions during
which gadolinium (Gd)-enhanced MRI scans were performed. The number of Gd-enhanced
lesions was significantly correlated with CSF cell counts, as well as the number of CD4+ …