An evaluation of transmitral and pulmonary venous Doppler indices for assessing murine left ventricular diastolic function
L Yuan, T Wang, F Liu, ED Cohen, VV Patel - Journal of the American …, 2010 - Elsevier
With the continued development of genetically engineered mouse models of cardiac
disease, further advancement of noninvasive techniques for evaluating cardiac diastolic
dysfunction in these models would be valuable. Therefore, we performed comprehensive
transmitral and pulmonary venous Doppler echocardiographic studies to devise novel
indices of diastolic function in a mouse model with cardiac hypertrophy, which were
validated against invasively measured hemodynamic parameters. We examined 10 HopXTg …
disease, further advancement of noninvasive techniques for evaluating cardiac diastolic
dysfunction in these models would be valuable. Therefore, we performed comprehensive
transmitral and pulmonary venous Doppler echocardiographic studies to devise novel
indices of diastolic function in a mouse model with cardiac hypertrophy, which were
validated against invasively measured hemodynamic parameters. We examined 10 HopXTg …