Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells
NM Curthoys, H Freittag, A Connor, M Desouza… - Molecular and Cellular …, 2014 - Elsevier
Background The actin cytoskeleton is critically involved in the regulation of neurite
outgrowth. Results The actin cytoskeleton-associated protein tropomyosin induces neurite
outgrowth in B35 neuroblastoma cells and regulates neurite branching in an isoform-
dependent manner. Conclusions Our data indicate that tropomyosins are key regulators of
the actin cytoskeleton during neurite outgrowth. Significance Revealing the molecular
machinery that regulates the actin cytoskeleton during neurite outgrowth may provide new …
outgrowth. Results The actin cytoskeleton-associated protein tropomyosin induces neurite
outgrowth in B35 neuroblastoma cells and regulates neurite branching in an isoform-
dependent manner. Conclusions Our data indicate that tropomyosins are key regulators of
the actin cytoskeleton during neurite outgrowth. Significance Revealing the molecular
machinery that regulates the actin cytoskeleton during neurite outgrowth may provide new …