Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes.
Pax genes encode a family of developmentally regulated transcription factors that have
been implicated in a number of human and murine congenital disorders, as well as in
tumorigenesis (Gruss, P., and Walther, C.(1992) Cell 69, 719-722; Hill, R., and van
Heyningen, V.(1992) Trends Genet. 8, 119-120; Chalepakis, G., Tremblay, P., and Gruss,
P.(1992) J. Cell Sci. Suppl. 16, 61-67; Maulbecker, CC, and Gruss, P.(1993) EMBO J. 12,
2361-2367; Walther, C., Guenet, JL, Simon, D., Deutsch, U., Jostes, B., Goulding, MD …
been implicated in a number of human and murine congenital disorders, as well as in
tumorigenesis (Gruss, P., and Walther, C.(1992) Cell 69, 719-722; Hill, R., and van
Heyningen, V.(1992) Trends Genet. 8, 119-120; Chalepakis, G., Tremblay, P., and Gruss,
P.(1992) J. Cell Sci. Suppl. 16, 61-67; Maulbecker, CC, and Gruss, P.(1993) EMBO J. 12,
2361-2367; Walther, C., Guenet, JL, Simon, D., Deutsch, U., Jostes, B., Goulding, MD …