Vitamin D effects on pregnancy and the placenta

JS Shin, MY Choi, MS Longtine, DM Nelson - Placenta, 2010 - Elsevier
Vitamin D is a pleiotropic secosteroid hormone important for health and disease prevention.
The actions of vitamin D are mediated by the vitamin D receptor that binds the active form of
vitamin D [1, 25 (OH) 2D] to induce both transcriptional and non-genomic responses.
Vitamin D has well known classical functions in calcium uptake and bone metabolism, but
more recent work highlights the importance of the nonclassical actions of vitamin D in a
variety of cell types. These actions include modulation of the innate and adaptive immune …