Coat proteins: shaping membrane transport
JS Bonifacino, J Lippincott-Schwartz - Nature reviews Molecular cell …, 2003 - nature.com
JS Bonifacino, J Lippincott-Schwartz
Nature reviews Molecular cell biology, 2003•nature.comCoat proteins allow the selective transfer of macromolecules from one membrane-enclosed
compartment to another by concentrating macromolecules into specialized membrane
patches and then deforming these patches into small coated vesicles. Recent findings
indicate that coat proteins might also participate in the differentiation of membrane domains
within organelles and large transport carriers, as well as in the association of the carriers
with the cytosketelon and with acceptor organelles.
compartment to another by concentrating macromolecules into specialized membrane
patches and then deforming these patches into small coated vesicles. Recent findings
indicate that coat proteins might also participate in the differentiation of membrane domains
within organelles and large transport carriers, as well as in the association of the carriers
with the cytosketelon and with acceptor organelles.
Abstract
Coat proteins allow the selective transfer of macromolecules from one membrane-enclosed compartment to another by concentrating macromolecules into specialized membrane patches and then deforming these patches into small coated vesicles. Recent findings indicate that coat proteins might also participate in the differentiation of membrane domains within organelles and large transport carriers, as well as in the association of the carriers with the cytosketelon and with acceptor organelles.
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