[HTML][HTML] The role of apoptosis signal-regulating kinase 1 in lymphotoxin-β receptor-mediated cell death

MC Chen, MJ Hwang, YC Chou, WH Chen… - Journal of Biological …, 2003 - ASBMB
LIGHT (homologous tolymphotoxins, shows inducible expression, and competes with
herpes simplex virus glycoprotein D forherpesvirus entry mediator, a receptor expressed byT
lymphocytes) is a member of the tumor necrosis factor superfamily that can interact with
lymphotoxin-β receptor (LTβR), herpes virus entry mediator, and decoy receptor (DcR3). In
our previous study, we showed that LIGHT is able to induce cell death via the non-death
domain containing receptor LTβR to activate both caspase-dependent and caspase …