[HTML][HTML] Stem cells and DNA damage: persist or perish?
AA Lane, DT Scadden - Cell, 2010 - cell.com
Cell, 2010•cell.com
Stem cells repopulate tissues after injury while also renewing themselves, but this makes
them vulnerable to genotoxic damage. Mohrin et al.(2010) and Milyavsky et al.(2010) now
show that mouse and human hematopoietic stem cells make opposing decisions about
whether to die or to persist in response to DNA damage.
them vulnerable to genotoxic damage. Mohrin et al.(2010) and Milyavsky et al.(2010) now
show that mouse and human hematopoietic stem cells make opposing decisions about
whether to die or to persist in response to DNA damage.
Stem cells repopulate tissues after injury while also renewing themselves, but this makes them vulnerable to genotoxic damage. Mohrin et al. (2010) and Milyavsky et al. (2010) now show that mouse and human hematopoietic stem cells make opposing decisions about whether to die or to persist in response to DNA damage.
cell.com