Organization, chemistry, and assembly of the cytoskeletal apparatus of the intestinal brush border

MS Mooseker - Annual review of cell biology, 1985 - annualreviews.org
MS Mooseker
Annual review of cell biology, 1985annualreviews.org
The cytoskeletal apparatus which underlies and supports the apical, brush border (BB)
surface of the intestinal epithelial cell is among the most highly ordered arrays of actin
filaments and associated proteins in nature. In addition, the BB, and subfractions such as
microvilli (MV)(Bretscher & Weber 1978b), can be isolated in quantities sufficient for
biochemical and structural studies. For these reasons the BB has been the subject of
intensive scrutiny over the past decade. There are several reviews on the BB cytoskeleton …
The cytoskeletal apparatus which underlies and supports the apical, brush border (BB) surface of the intestinal epithelial cell is among the most highly ordered arrays of actin filaments and associated proteins in nature. In addition, the BB, and subfractions such as microvilli (MV)(Bretscher & Weber 1978b), can be isolated in quantities sufficient for biochemical and structural studies. For these reasons the BB has been the subject of intensive scrutiny over the past decade. There are several reviews on the BB cytoskeleton (Mooseker & Howe 1982; Bretscher 1983a; Mooseker 1983),
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