[PDF][PDF] The Degree of Macrophage Infiltration into the Cancer Cell Nest is a Significant Predictor

S Ohno, H Inagawa, DK Dhar - Anticancer research, 2003 - researchgate.net
Background: Tumor-associated macrophages (TAMs) have varying functions depending on
the microenvironment of tumor tissue. Je studied the biological role of TAMs in gastric
cancer on the basis of their spatial disribution in the cancer tissue. Materials and Methods:
Tissue specimens foin 84 advanced gastric carcinoma (pT2; 41 cases, pT3;-43 cases)
patients who had undergone a curative resection were stained for TAM (CD68+ cells),
incidence of tumor cell apoptosis (TUNEL) and host inmune status (CD8+ T cells). CD68+ …