[HTML][HTML] The alveolar macrophages in asthma: a double-edged sword

J Balhara, AS Gounni - Mucosal immunology, 2012 - Elsevier
Asthma is a complex disease of the lungs, which is characterized by airway inflammation
and airway hyperresponsiveness (AHR). Alveolar macrophages (AMs), one of the prominent
immune system cells found in the airways, have been implicated in the development and
progression of asthma. AMs constitute a unique subset of pulmonary macrophages, which
serve as a first line of defense against foreign invaders to the lung tissue. In addition, based
on human and animal studies, they have also been found to regulate pro-and anti …