Antiphospholipid syndrome is characterised by a variety of clinical and immunological
manifestations. The clinical hallmarks of this syndrome are thrombosis and poor obstetric
outcomes, including miscarriages, fetal loss and severe pre-eclampsia. The main
antiphospholipid antibodies include lupus anticoagulant, anticardiolipin and anti-β2-
glycoprotein I. The combination of aspirin and heparin is considered the standard of care for
women with antiphospholipid syndrome and embryo–fetal losses; however, aspirin in …