[HTML][HTML] In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4+ T cells in acute HIV-1 infection
RL Sabado, DG Kavanagh, DE Kaufmann, K Fru… - PLoS One, 2009 - ncbi.nlm.nih.gov
RL Sabado, DG Kavanagh, DE Kaufmann, K Fru, E Babcock, E Rosenberg, B Walker…
PLoS One, 2009•ncbi.nlm.nih.govBackground The requirements for priming of HIV-specific T cell responses initially seen in
infected individuals remain to be defined. Activation of T cell responses in lymph nodes
requires cell-cell contact between T cells and DCs, which can give concurrent activation of T
cells and HIV transmission.
infected individuals remain to be defined. Activation of T cell responses in lymph nodes
requires cell-cell contact between T cells and DCs, which can give concurrent activation of T
cells and HIV transmission.
Abstract
Background
The requirements for priming of HIV-specific T cell responses initially seen in infected individuals remain to be defined. Activation of T cell responses in lymph nodes requires cell-cell contact between T cells and DCs, which can give concurrent activation of T cells and HIV transmission.
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