Interpreting studies of interactions between RA risk factors

EW Karlson, KH Costenbader - Nature Reviews Rheumatology, 2010 - nature.com
EW Karlson, KH Costenbader
Nature Reviews Rheumatology, 2010nature.com
Interactions between HLA and PTPN22 genotypes and smoking have been implicated in
overall susceptibility to rheumatoid arthritis as well as the incidence of particular disease
phenotypes in case–control and case-only studies. As recent epidemiological evidence
shows, deciphering these interactions demands consideration of the analytical approach
used.
Interactions between HLA and PTPN22 genotypes and smoking have been implicated in overall susceptibility to rheumatoid arthritis as well as the incidence of particular disease phenotypes in case–control and case-only studies. As recent epidemiological evidence shows, deciphering these interactions demands consideration of the analytical approach used.
nature.com