Neuropeptide Y polymorphism increases the risk for asthma in overweight subjects; protection from atherosclerosis in asthmatic subjects–The cardiovascular risk in …
U Jaakkola, T Kakko, M Juonala, T Lehtimäki, J Viikari… - Neuropeptides, 2012 - Elsevier
AIMS: The role of neuropeptide Y (NPY) and its gene polymorphisms in the development of
atherosclerosis has become increasingly evident. In asthma, NPY has been shown to be
involved as immunomodulator. In this study, we investigated the role of two functional NPY
polymorphisms, NPY-Leu7Pro (rs16139) and NPY-399C/T (rs16147) and obesity for the
development of asthma as well as atherosclerosis in asthmatic and non-asthmatic subjects.
Also, we measured heart rate variability (HRV) and NPY in serum since these might …
atherosclerosis has become increasingly evident. In asthma, NPY has been shown to be
involved as immunomodulator. In this study, we investigated the role of two functional NPY
polymorphisms, NPY-Leu7Pro (rs16139) and NPY-399C/T (rs16147) and obesity for the
development of asthma as well as atherosclerosis in asthmatic and non-asthmatic subjects.
Also, we measured heart rate variability (HRV) and NPY in serum since these might …