[HTML][HTML] Lymphatic endothelium: morphological, molecular and functional properties

MS Pepper, M Skobe - The Journal of cell biology, 2003 - ncbi.nlm.nih.gov
MS Pepper, M Skobe
The Journal of cell biology, 2003ncbi.nlm.nih.gov
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial
fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The
traditional view that lymphatic capillaries are passive participants in these tasks is currently
being challenged. This overview highlights recent advances in our understanding of the
molecular mechanisms underlying the formation and function of lymphatic vessels.
Abstract
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The traditional view that lymphatic capillaries are passive participants in these tasks is currently being challenged. This overview highlights recent advances in our understanding of the molecular mechanisms underlying the formation and function of lymphatic vessels.
ncbi.nlm.nih.gov