Vitamin D and intestinal calcium transport: facts, speculations and hypotheses

RH Wasserman, CS Fullmer - The Journal of nutrition, 1995 - Elsevier
The intestinal absorption of Ca 2+ occurs by both a saturable, transcellular process and a
non-saturable, paracellular path. The transcellular path is a multistep process, comprised of
the transfer of luminal Ca 2+ into the enterocyte, the translocation of Ca 2+ from point of
entry (the microvillus border or membrane) to the basolateral membrane, and the active
extrusion from the cell into the circulatory system. Each step in the transcellular movement of
Ca 2+ has a vitamin D-dependent component. The paracellular path also appears to be …