[HTML][HTML] Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse
T Geiger, A Velic, B Macek, E Lundberg… - Molecular & Cellular …, 2013 - ASBMB
Identifying the building blocks of mammalian tissues is a precondition for understanding
their function. In particular, global and quantitative analysis of the proteome of mammalian
tissues would point to tissue-specific mechanisms and place the function of each protein in a
whole-organism perspective. We performed proteomic analyses of 28 mouse tissues using
high-resolution mass spectrometry and used a mix of mouse tissues labeled via stable
isotope labeling with amino acids in cell culture as a" spike-in" internal standard for accurate …
their function. In particular, global and quantitative analysis of the proteome of mammalian
tissues would point to tissue-specific mechanisms and place the function of each protein in a
whole-organism perspective. We performed proteomic analyses of 28 mouse tissues using
high-resolution mass spectrometry and used a mix of mouse tissues labeled via stable
isotope labeling with amino acids in cell culture as a" spike-in" internal standard for accurate …