Acute cellular rejection is a risk factor for bronchiolitis obliterans syndrome independent of post-transplant baseline FEV1
BACKGROUND: Post-transplant baseline forced expiratory volume in 1 second (FEV1)
constitutes a systematic bias in analyses of bronchiolitis obliterans syndrome (BOS). This
retrospective study evaluates risk factors for BOS adjusting for the confounding of post-
transplant baseline FEV1. METHODS: A multivariate survival and competing risk analysis of
a large consecutive series of patients (n= 389) from a national center 1992 to 2004.
Exclusion criteria were patients not surviving at least 3 months after transplantation (n= 39) …
constitutes a systematic bias in analyses of bronchiolitis obliterans syndrome (BOS). This
retrospective study evaluates risk factors for BOS adjusting for the confounding of post-
transplant baseline FEV1. METHODS: A multivariate survival and competing risk analysis of
a large consecutive series of patients (n= 389) from a national center 1992 to 2004.
Exclusion criteria were patients not surviving at least 3 months after transplantation (n= 39) …