Maternal cigarette smoking, metabolic gene polymorphism, and infant birth weight
X Wang, B Zuckerman, C Pearson, G Kaufman, C Chen… - Jama, 2002 - jamanetwork.com
ContextLittle is known about genetic susceptibility to cigarette smoke in relation to adverse
pregnancy outcomes. ObjectiveTo investigate whether the association between maternal
cigarette smoking and infant birth weight differs by polymorphisms of 2 maternal metabolic
genes: CYP1A1 and GSTT1. Design, Setting, and ParticipantsCase-control study conducted
in 1998-2000 among 741 mothers (174 ever smokers and 567 never smokers) who
delivered singleton live births at Boston Medical Center. A total of 207 cases were preterm or …
pregnancy outcomes. ObjectiveTo investigate whether the association between maternal
cigarette smoking and infant birth weight differs by polymorphisms of 2 maternal metabolic
genes: CYP1A1 and GSTT1. Design, Setting, and ParticipantsCase-control study conducted
in 1998-2000 among 741 mothers (174 ever smokers and 567 never smokers) who
delivered singleton live births at Boston Medical Center. A total of 207 cases were preterm or …