Experience with synthetic vaccines for cancer and persistent virus infections in nonhuman primates and patients
ED Quakkelaar, CJM Melief - Advances in immunology, 2012 - Elsevier
Synthetic vaccines, in particular long synthetic peptides of approximately 25–50 amino acids
in length, are attractive for HIV vaccine development and for induction of therapeutic immune
responses in patients with (pre-) malignant disorders. In the case of preventive vaccine
development against HIV, no major success has been achieved, but the possibilities are by
no means exhausted. A long peptide vaccine consisting of 13 overlapping peptides, which
together cover the entire length of the two oncogenic proteins E6 and E7 of high-risk human …
in length, are attractive for HIV vaccine development and for induction of therapeutic immune
responses in patients with (pre-) malignant disorders. In the case of preventive vaccine
development against HIV, no major success has been achieved, but the possibilities are by
no means exhausted. A long peptide vaccine consisting of 13 overlapping peptides, which
together cover the entire length of the two oncogenic proteins E6 and E7 of high-risk human …