[HTML][HTML] Cloning and characterization of mouse lung-type acyl-CoA: lysophosphatidylcholine acyltransferase 1 (LPCAT1): expression in alveolar type II cells and …
H Nakanishi, H Shindou, D Hishikawa… - Journal of Biological …, 2006 - ASBMB
Phosphatidylcholine (1, 2-diacyl-sn-glycero-3-phosphocholine, PC), is an important
constituent of biological membranes. It is also the major component of serum lipoproteins
and pulmonary surfactant. In the remodeling pathway of PC biosynthesis, 1-acyl-sn-glycero-
3-phosphocholine (LPC) is converted to PC by acyl-CoA: lysophosphatidylcholine
acyltransferase (LPCAT, EC 2.3. 1.23). Whereas LPCAT activity has been detected in
several tissues, the structure and detailed biochemical information on the enzyme have not …
constituent of biological membranes. It is also the major component of serum lipoproteins
and pulmonary surfactant. In the remodeling pathway of PC biosynthesis, 1-acyl-sn-glycero-
3-phosphocholine (LPC) is converted to PC by acyl-CoA: lysophosphatidylcholine
acyltransferase (LPCAT, EC 2.3. 1.23). Whereas LPCAT activity has been detected in
several tissues, the structure and detailed biochemical information on the enzyme have not …