Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator
R Kubota, NL Boman, R David, S Mallikaarjun, S Patil… - Retina, 2012 - journals.lww.com
Retina, 2012•journals.lww.com
SAFETY AND EFFECT ON ROD FUNCTION OF ACU-4429, A NOVEL SMALL... : RETINA
SAFETY AND EFFECT ON ROD FUNCTION OF ACU-4429, A NOVEL SMALL-MOLECULE
VISUAL CYCLE MODULATOR : RETINA Log in or Register Subscribe to journalSubscribe Get
new issue alertsGet alerts Secondary Logo Journal Logo Advanced Search Toggle navigation
Subscribe Register Login Articles & Issues Published Ahead-of-Print Collections Supplements
Videos Podcasts For Authors Journal Info Advanced Search January 2012 - Volume 32 - Issue …
SAFETY AND EFFECT ON ROD FUNCTION OF ACU-4429, A NOVEL SMALL-MOLECULE
VISUAL CYCLE MODULATOR : RETINA Log in or Register Subscribe to journalSubscribe Get
new issue alertsGet alerts Secondary Logo Journal Logo Advanced Search Toggle navigation
Subscribe Register Login Articles & Issues Published Ahead-of-Print Collections Supplements
Videos Podcasts For Authors Journal Info Advanced Search January 2012 - Volume 32 - Issue …
Background:
ACU-4429 is a first in class small-molecule visual cycle modulator that inhibits the isomerase complex and, in mouse models of retinal degeneration, prevents the accumulation of A2E.
Lippincott Williams & Wilkins