Elsevier Trophoblast Research Award Lecture: Unique properties of decidual T cells and their role in immune regulation during human pregnancy
T Tilburgs, FHJ Claas, SA Scherjon - Placenta, 2010 - Elsevier
Maternal lymphocytes at the fetal–maternal interface play a key role in the immune
acceptance of the allogeneic fetus. Most studies focus on decidual NK cells and their
interaction with fetal trophoblasts, whereas limited data are available on the mechanisms of
fetus specific immune recognition and immune regulation by decidual T cells at the fetal–
maternal interface. The aim of this review is to describe the phenotypic characteristics of
decidual T cell subsets present at the fetal–maternal interface, their interaction with HLA-C …
acceptance of the allogeneic fetus. Most studies focus on decidual NK cells and their
interaction with fetal trophoblasts, whereas limited data are available on the mechanisms of
fetus specific immune recognition and immune regulation by decidual T cells at the fetal–
maternal interface. The aim of this review is to describe the phenotypic characteristics of
decidual T cell subsets present at the fetal–maternal interface, their interaction with HLA-C …