[PDF][PDF] Self-propagation and transmission of misfolded mutant SOD1: prion or prion-like phenomenon?
C Münch, A Bertolotti - Cell Cycle, 2011 - Taylor & Francis
C Münch, A Bertolotti
Cell Cycle, 2011•Taylor & FrancisSelf-propagation and transmission of misfolded mutant SOD1: Prion or prion-like phenomenon?
Page 1 www.landesbioscience.com Cell Cycle 1711 Cell Cycle 10:11, 1711-1711; June 1,
2011; © 2011 Landes Bioscience CeLL CyCLe Feature CeLL CyCLe Feature The hallmark of
both sporadic and familial forms of amyotrophic lateral sclerosis (ALS), a common and inevitably
fatal motor neuron disease, is the presence of proteinaceous deposits in motor neurons.
Mutations in the gene encoding the abundantly expressed cytosolic superoxide dismutase-1 …
Page 1 www.landesbioscience.com Cell Cycle 1711 Cell Cycle 10:11, 1711-1711; June 1,
2011; © 2011 Landes Bioscience CeLL CyCLe Feature CeLL CyCLe Feature The hallmark of
both sporadic and familial forms of amyotrophic lateral sclerosis (ALS), a common and inevitably
fatal motor neuron disease, is the presence of proteinaceous deposits in motor neurons.
Mutations in the gene encoding the abundantly expressed cytosolic superoxide dismutase-1 …
Comment on: Münch C, et al. Proc Natl Acad Sci USA 2011; 108:3548-53.
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