mRNA stability in eukaryotes
P Mitchell, D Tollervey - Current opinion in genetics & development, 2000 - Elsevier
Current opinion in genetics & development, 2000•Elsevier
During the past two years, the role of the proteins HuR and hnRNP D in regulated mRNA
degradation in humans has become clearer, and a putative mRNA deadenylase, DAN or
PARN, has been identified. In yeast, the relationship between translation and mRNA
turnover is clearer, but the mRNA decapping process has turned out to be unexpectedly
complex.
degradation in humans has become clearer, and a putative mRNA deadenylase, DAN or
PARN, has been identified. In yeast, the relationship between translation and mRNA
turnover is clearer, but the mRNA decapping process has turned out to be unexpectedly
complex.
During the past two years, the role of the proteins HuR and hnRNP D in regulated mRNA degradation in humans has become clearer, and a putative mRNA deadenylase, DAN or PARN, has been identified. In yeast, the relationship between translation and mRNA turnover is clearer, but the mRNA decapping process has turned out to be unexpectedly complex.
Elsevier