[CITATION][C] An imprinted antisense RNA overlaps UBE3A and a second maternally expressed transcript
C Rougeulle, C Cardoso, M Fontés, L Colleaux… - Nature …, 1998 - nature.com
An imprinted antisense RNA overlaps UBE3A and a second maternally expressed transcript
Page 1 © 1998 Nature Publishing Group http://www.nature.com/naturegenetics peutic levels
and should be life-long and suitable for the treatment of genetic diseases. The mechanism
which results in a relatively small percentage of hepatocytes containing multiple rAAV genomes
will require further study. Perhaps a threshold amount of vector genome and/or the presence
of an as yet unknown cellular milieu is required for integration. Acknowledgements We thank …
Page 1 © 1998 Nature Publishing Group http://www.nature.com/naturegenetics peutic levels
and should be life-long and suitable for the treatment of genetic diseases. The mechanism
which results in a relatively small percentage of hepatocytes containing multiple rAAV genomes
will require further study. Perhaps a threshold amount of vector genome and/or the presence
of an as yet unknown cellular milieu is required for integration. Acknowledgements We thank …