Lung stem and progenitor cells in tissue homeostasis and disease

KT Leeman, CM Fillmore, CF Kim - Current topics in developmental biology, 2014 - Elsevier
The mammalian lung is a complex organ containing numerous putative stem/progenitor cell
populations that contribute to region-specific tissue homeostasis and repair. In this review,
we discuss recent advances in identifying and studying these cell populations in the context
of lung homeostasis and disease. Genetically engineered mice now allow for lineage tracing
of several lung stem and progenitor cell populations in vivo during different types of lung
injury repair. Using specific sets of cell surface markers, these cells can also be isolated from …