DNA methylation dynamics in health and disease
Y Bergman, H Cedar - Nature structural & molecular biology, 2013 - nature.com
Y Bergman, H Cedar
Nature structural & molecular biology, 2013•nature.comDNA methylation is an epigenetic mark that is erased in the early embryo and then re-
established at the time of implantation. In this Review, dynamics of DNA methylation during
normal development in vivo are discussed, starting from fertilization through embryogenesis
and postnatal growth, as well as abnormal methylation changes that occur in cancer.
established at the time of implantation. In this Review, dynamics of DNA methylation during
normal development in vivo are discussed, starting from fertilization through embryogenesis
and postnatal growth, as well as abnormal methylation changes that occur in cancer.
Abstract
DNA methylation is an epigenetic mark that is erased in the early embryo and then re-established at the time of implantation. In this Review, dynamics of DNA methylation during normal development in vivo are discussed, starting from fertilization through embryogenesis and postnatal growth, as well as abnormal methylation changes that occur in cancer.
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