[HTML][HTML] Angiotensin-II and MARCKS: a hydrogen peroxide-and RAC1-dependent signaling pathway in vascular endothelium
H Kalwa, JL Sartoretto, SM Sartoretto… - Journal of Biological …, 2012 - ASBMB
MARCKS is an actin-binding protein that modulates vascular endothelial cell migration and
cytoskeleton signaling (Kalwa, H., and Michel, T.(2011) J. Biol. Chem. 286, 2320–2330).
Angiotensin-II is a vasoactive peptide implicated in vascular physiology as well as
pathophysiology; the pathways connecting angiotensin-II and cytoskeletal remodeling are
incompletely understood. Here we show that MARCKS is expressed in intact arterial
preparations, with prominent staining of the endothelium. In endothelial cells, angiotensin-II …
cytoskeleton signaling (Kalwa, H., and Michel, T.(2011) J. Biol. Chem. 286, 2320–2330).
Angiotensin-II is a vasoactive peptide implicated in vascular physiology as well as
pathophysiology; the pathways connecting angiotensin-II and cytoskeletal remodeling are
incompletely understood. Here we show that MARCKS is expressed in intact arterial
preparations, with prominent staining of the endothelium. In endothelial cells, angiotensin-II …