Imaging the nigrostriatal system to monitor disease progression and treatment-induced complications

R Kuriakose, AJ Stoessl - Progress in brain research, 2010 - Elsevier
Radiotracer imaging (RTI) techniques such as positron emission tomography (PET) allow
the in vivo assessment of nigrostriatal DA function in Parkinson's disease and have provided
valuable insights into the mechanisms of nigrostriatal degeneration and the consequent
compensatory changes. Moreover, functional imaging serves as an excellent tool in the
assessment of the progression of PD and the evolution of treatment-related complications.
However, various studies have shown discordance between clinical progression of PD and …