[HTML][HTML] Regulation of actin cytoskeleton dynamics in cells

SH Lee, R Dominguez - Molecules and cells, 2010 - Elsevier
The dynamic remolding of the actin cytoskeleton is a critical part of most cellular activities,
and malfunction of cytoskeletal proteins results in various human diseases. The transition
between two forms of actin, monomeric or G-actin and filamentous or F-actin, is tightly
regulated in time and space by a large number of signaling, scaffolding and actinbinding
proteins (ABPs). New ABPs are constantly being discovered in the post-genomic era. Most
of these proteins are modular, integrating actin binding, protein-protein interaction …