Future therapies for Hirschsprung's disease
DJ Wilkinson, DH Edgar, SE Kenny - Seminars in pediatric surgery, 2012 - Elsevier
The current management of Hirschsprung's disease (HSCR) is still associated with
significant long-term morbidities despite on-going refinements in surgical care. Over the
course of the past 20 years, significant inroads have been made in our understanding of the
development of the enteric nervous system and what factors are responsible for the
development of HSCR. This has prompted increased interest in the possibility of using this
knowledge to develop new alternative and adjunctive therapies for HSCR. The aim of this …
significant long-term morbidities despite on-going refinements in surgical care. Over the
course of the past 20 years, significant inroads have been made in our understanding of the
development of the enteric nervous system and what factors are responsible for the
development of HSCR. This has prompted increased interest in the possibility of using this
knowledge to develop new alternative and adjunctive therapies for HSCR. The aim of this …