[HTML][HTML] Linoleic acid induces calcium signaling, Src kinase phosphorylation, and neurotransmitter release in mouse CD36-positive gustatory cells
We have recently demonstrated that the cells expressing CD36, localized apically on the
taste buds of mouse lingual circumvallate papillae, act as gustatory cells. In the present
study we isolated these CD36-positive cells from mouse circumvallate papillae and
investigated intracellular signaling events, triggered by a long-chain polyunsaturated fatty
acid, ie linoleic acid (LA). LA induced increases in free intracellular calcium
concentrations,[Ca 2+] i, by recruiting calcium from endoplasmic reticulum pool via inositol 1 …
taste buds of mouse lingual circumvallate papillae, act as gustatory cells. In the present
study we isolated these CD36-positive cells from mouse circumvallate papillae and
investigated intracellular signaling events, triggered by a long-chain polyunsaturated fatty
acid, ie linoleic acid (LA). LA induced increases in free intracellular calcium
concentrations,[Ca 2+] i, by recruiting calcium from endoplasmic reticulum pool via inositol 1 …