An improved method for the detection of peptide-induced upregulation of HLA-A2 molecules on TAP-deficient T2 cells.
M Regner, MH Claesson, S Bregenholt… - Experimental and …, 1996 - europepmc.org
M Regner, MH Claesson, S Bregenholt, M Röpke
Experimental and clinical immunogenetics, 1996•europepmc.orgPeptide-induced upregulation of MHC class I on TAP-deficient T2 cells is used to monitor
peptide binding to class I molecules. We present a temperature-dependent modification of
the T2 assay which increases the sensitivity of peptide binding to MHC class I with several
orders of magnitude.
peptide binding to class I molecules. We present a temperature-dependent modification of
the T2 assay which increases the sensitivity of peptide binding to MHC class I with several
orders of magnitude.
Peptide-induced upregulation of MHC class I on TAP-deficient T2 cells is used to monitor peptide binding to class I molecules. We present a temperature-dependent modification of the T2 assay which increases the sensitivity of peptide binding to MHC class I with several orders of magnitude.
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