Lung endotoxemia is characterized by neutrophil accumulation, increased vascular
permeability and parenchymal injury. This can also affect the endogenous pathways that
operate in the host to keep inflammation under control. Here, we demonstrate differential
expression of annexin-A1 (AnxA1) protein in mice after the local or intraperitoneal
administration of lipopolysaccharide (LPS; 1 mg/kg) in mice and the regulation of the
endotoxemic inflammation after the pre-treatment with the AnxA1 peptidomimetic Ac2-26 …