[HTML][HTML] Coregulator codes of transcriptional regulation by nuclear receptors
MG Rosenfeld, CK Glass - Journal of Biological Chemistry, 2001 - ASBMB
Members of the nuclear receptor superfamily directly activate or repress target genes by
binding to hormone response elements (HREs) 1 in promoter or enhancer regions, and by
binding to other DNA sequence-specific activators and can inhibit the transcriptional
activities of other classes of transcription factors by transrepression. Hormone response
elements provide specificity to receptor homodimer heterodimer binding (reviewed in Ref.
2). Nuclear receptor functions are directed by specific activation domains, referred to as …
binding to hormone response elements (HREs) 1 in promoter or enhancer regions, and by
binding to other DNA sequence-specific activators and can inhibit the transcriptional
activities of other classes of transcription factors by transrepression. Hormone response
elements provide specificity to receptor homodimer heterodimer binding (reviewed in Ref.
2). Nuclear receptor functions are directed by specific activation domains, referred to as …