Immunolocalization of farnesoid X receptor (FXR) in mouse tissues using tissue microarray

H Higashiyama, M Kinoshita, S Asano - Acta histochemica, 2008 - Elsevier
Farnesoid X receptor (FXR) is a member of the nuclear receptor family and is known to play
important roles in bile acid homeostasis, and lipid and glucose metabolism. In this study, to
elucidate the systemic physiological functions of FXR, comprehensive immunohistochemical
analysis of cell/subcellualr localization of FXR and its heterodimmer partner, retinoid X
receptor (RXR)-alpha, in adult mice tissues was performed using tissue microarray (TMA)-
based immunohistochemistry. FXR immunolabeling was observed in the enterohepatic …