Previous work has shown that gluconeogenesis from a variety of substrates is stimulated by
oleate. This paper reports data on the effect of oleate on tissue levels of coenzyme A
derivatives, ketone bodies, citric acid cycle intermediates, and adenine nucleotides in rat
livers perfused with alanine, lactate, or pyruvate. The effect of oleate on the activity of the
citric acid cycle with lactate as substrate has been assessed from measurements of the
oxygen consumption, and the rates of production or utilization of lactate, pyruvate, glucose …