[HTML][HTML] Synaptotagmin‐like protein 4 and Rab8 interact and increase dense granule release in platelets
A Hampson, A O'connor, A Smolenski - Journal of Thrombosis and …, 2013 - Elsevier
Background: Platelets are highly specialized cells that regulate hemostasis and thrombosis
in the vasculature. Upon activation, platelets release various granules that impact on
platelets, the coagulation system, other blood cells and the vessel wall; however, the
mechanisms controlling granule release are only partially known. We have shown
previously that synaptotagmin‐like protein (Slp) 1 decreases dense granule release in
platelets. Objectives: To determine the role of other Slps and their binding partners on …
in the vasculature. Upon activation, platelets release various granules that impact on
platelets, the coagulation system, other blood cells and the vessel wall; however, the
mechanisms controlling granule release are only partially known. We have shown
previously that synaptotagmin‐like protein (Slp) 1 decreases dense granule release in
platelets. Objectives: To determine the role of other Slps and their binding partners on …