Clostridium difficile-associated disease (CDAD) is the major known cause of antibiotic-
induced diarrhea and colitis, and the disease is thought to result from persistent disruption of
commensal gut microbiota. Bacteriotherapy by way of fecal transplantation can be used to
treat recurrent CDAD, which is thought to reestablish the normal colonic microflora.
However, limitations of conventional microbiologic techniques have, until recently,
precluded testing of this idea. In this study, we used terminal-restriction fragment length …