Fibronectin fibrillogenesis: a paradigm for extracellular matrix assembly

JE Schwarzbauer, JL Sechler - Current opinion in cell biology, 1999 - Elsevier
JE Schwarzbauer, JL Sechler
Current opinion in cell biology, 1999Elsevier
Fibronectin matrix assembly is a regulated stepwise process. In the past year, analyses of
fibronectin domains, integrin and cytoskeletal contributions, and fibril architecture have
provided new insights into assembly mechanisms and matrix control of cell functions. Like
fibronectin, laminin polymerization is cell-mediated. Thus a common pathway for
extracellular matrix assembly is emerging.
Fibronectin matrix assembly is a regulated stepwise process. In the past year, analyses of fibronectin domains, integrin and cytoskeletal contributions, and fibril architecture have provided new insights into assembly mechanisms and matrix control of cell functions. Like fibronectin, laminin polymerization is cell-mediated. Thus a common pathway for extracellular matrix assembly is emerging.
Elsevier