Longistatin, a novel EF-hand protein from the ixodid tick Haemaphysalis longicornis, is required for acquisition of host blood-meals

MK Islam, T Miyoshi, MA Alim, T Hatta, K Yamaji… - International journal for …, 2010 - Elsevier
Calcium and the EF-hand Ca++-binding proteins have been undisputedly recognised as the
key players in almost all aspect of cell functions, starting from the cell's birth, during mitosis
to its end with apoptosis. But in a few exceptional cases the EF-hand proteins are secreted
from the cells and play their crucial roles extracellularly. Here, to our knowledge for the first
time, we have identified and characterised an EF-hand Ca++-binding protein from the
salivary glands of the ixodid tick, Haemaphysalis longicornis, herein called longistatin …