Stem cell fate and patterning in mammalian epidermis
FM Watt - Current opinion in genetics & development, 2001 - Elsevier
FM Watt
Current opinion in genetics & development, 2001•ElsevierRecent studies highlight characteristics of epidermal stem cells that were not fully
appreciated before. Stem cells are multipotential and signals exchanged with their
neighbours help to regulate exit from the stem cell compartment and differentiation along
specific lineages. Stem cells exhibit a high degree of spatial organisation, and cell clustering
and motility contribute to the assembly and maintenance of the epidermis.
appreciated before. Stem cells are multipotential and signals exchanged with their
neighbours help to regulate exit from the stem cell compartment and differentiation along
specific lineages. Stem cells exhibit a high degree of spatial organisation, and cell clustering
and motility contribute to the assembly and maintenance of the epidermis.
Recent studies highlight characteristics of epidermal stem cells that were not fully appreciated before. Stem cells are multipotential and signals exchanged with their neighbours help to regulate exit from the stem cell compartment and differentiation along specific lineages. Stem cells exhibit a high degree of spatial organisation, and cell clustering and motility contribute to the assembly and maintenance of the epidermis.
Elsevier